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1

Micro Reactors: Principles and Applications in Organic Synthesis.

Paul D. I. Fletcher, Stephen J. Haswell, Esteban Pombo-Villar, Brian H. Warrington, Paul Watts, Stephanie Y. F. Wong, Xunli Zhang

Journal:

Year:

2002

File:

PDF, 26 KB

2002

2

Microwave promoted rapid nitration of phenolic compounds with calcium nitrate

Ajay K. Bose, Subhendu N. Ganguly, Maghar S. Manhas, Sheetal Rao, Jeffrey Speck, Uri Pekelny, Esteban Pombo-Villars

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 88 KB

english, 2006

3

Micro reactors: principles and applications in organic synthesis

Paul D.I. Fletcher, Stephen J. Haswell, Esteban Pombo-Villar, Brian H. Warrington, Paul Watts, Stephanie Y.F. Wong, Xunli Zhang

Journal:

Year:

2002

Language:

english

File:

PDF, 1.01 MB

english, 2002

4

Solution phase synthesis of β-peptides using micro reactors

Paul Watts, Charlotte Wiles, Stephen J Haswell, Esteban Pombo-Villar

Journal:

Year:

2002

Language:

english

File:

PDF, 511 KB

english, 2002

5

Investigation of racemisation in peptide synthesis within a micro reactor

Watts, Paul, Wiles, Charlotte, Haswell, Stephen J., Pombo-Villar, Esteban

Journal:

Year:

2002

Language:

english

File:

PDF, 63 KB

english, 2002

6

Solid-State Structures and Racemization of Lithiated Schöllkopf's Bis[Lactim Ether]

Philip C. Andrews, Melissa Maguire, Esteban Pombo-Villar

Journal:

Helvetica Chimica Acta

Year:

2002

Language:

english

File:

PDF, 141 KB

english, 2002

7

ChemInform Abstract: Synthesis of N-Arylrolipram Derivatives — Potent and Selective Phosphodiesterase-IV Inhibitors — by Copper-Catalyzed Lactam—Aryl Halide Coupling.

Esther Aebischer, Edmond Bacher, F. W. Joachim Demnitz, Thomas H. Keller, Miriam Kurzmeyer, Marta L. Ortiz, Esteban Pombo-Villar, Hans-Peter Weber

Journal:

Year:

1999

File:

PDF, 30 KB

1999

8

ChemInform Abstract: Conjugate Additions of 1-Propenylphosphonates to Metalated Schoellkopf′s Bis-lactim Ether: Stereocontrolled Access to 2-Amino-3-methyl-4-phosphonobutanoic Acids.

Vicente Ojea, Maria Ruiz, Gideon Shapiro, Esteban Pombo-Villar

Journal:

Year:

2000

File:

PDF, 33 KB

2000

9

ChemInform Abstract: The Synthesis of Peptides Using Micro Reactors.

Paul Watts, Charlotte Wiles, Stephen J. Haswell, Esteban Pombo-Villar, Peter Styring

Journal:

Year:

2001

File:

PDF, 24 KB

2001

10

ChemInform Abstract: Synthesis and Structure—Activity Relationship of N-Arylrolipram Derivatives as Inhibitors of PDE4 Isozymes.

Thomas H. Keller, Katharine Bray-French, F. W. Joachim Demnitz, Thomas Mueller, Esteban Pombo-Villar, Christoph Walker

Journal:

Year:

2002

File:

PDF, 28 KB

2002

11

ChemInform Abstract: The Regioselective Preparation of 1,3-Diketones.

Charlotte Wiles, Paul Watts, Stephen J. Haswell, Esteban Pombo-Villar

Journal:

Year:

2002

File:

PDF, 29 KB

2002

12

ChemInform Abstract: The Regioselective Preparation of 1,3-Diketones within a Micro Reactor.

Charlotte Wiles, Paul Watts, Stephen J. Haswell, Esteban Pombo-Villar

Journal:

Year:

2002

File:

PDF, 28 KB

2002

13

Synthesis of Cyclopenta[b]indol-1-ones and Carbazol-4-ones from N-(2-Halophenyl)-Substituted Enaminones by Intramolecular Heck Reaction.

Ulrik S. Soerensen, Esteban Pombo-Villar

Journal:

Year:

2004

File:

PDF, 125 KB

2004

14

Copper-Free Palladium-Catalyzed Sonogashira-Type Coupling of Aryl Halides and 1-Aryl-2-(trimethylsilyl)acetylenes.

Ulrik S. Soerensen, Esteban Pombo-Villar

Journal:

Year:

2005

File:

PDF, 22 KB

2005

15

Synthesis and Structure of a Monomeric Chiral Lithium Dialkylaluminium Amide Derived from Schöllkopf’s Bis-lactim Ether and α-(Methylbenzyl)benzylamine

Philip C. Andrews, Melissa Maguire, Esteban Pombo-Villar

Journal:

European Journal of Inorganic Chemistry

Year:

2003

Language:

english

File:

PDF, 127 KB

english, 2003

16

Absolute Configuration of 3-Substituted 1-Azabicyclo[2.2.1]heptanes

Jakob Boelsterli, Ursula Eggnauer, Esteban Pombo-Villar, Hans-Peter Weber, Malcolm Walkinshaw, Robert O. Gould

Journal:

Helvetica Chimica Acta

Year:

1992

Language:

english

File:

PDF, 396 KB

english, 1992

17

Absolute Configuration of 2-Substituted 2-Azabicyclo[2.2.1]hept-5-enes

Esteban Pombo-Villar, Jakob Boelsterli, Maria Magdalena Cid, Julien France, Beat Fuchs, Malcolm Walkinshaw, Hans-Peter Weber

Journal:

Helvetica Chimica Acta

Year:

1993

Language:

english

File:

PDF, 781 KB

english, 1993

18

Enantioselective Synthesis of 3- Azabicyclo[4.3.0]nonane Alkaloids

Maria Magdalena Cid, Esteban Pombo-Villar

Journal:

Helvetica Chimica Acta

Year:

1993

Language:

english

File:

PDF, 1.25 MB

english, 1993

19

Chemie von α-Aminonitrilen. 13. Mitteilung. Über die Bildung von 2-Oxoethyl-phosphaten (“Glycoladehyd-phosphaten”) aus rac-Oxirancarbonitril und anorganischem Phosphat und über (formale) Konstitutionelle Zusammenhänge zwischen 2-Oxoethyl-phosphaten und Oligo (hexo- und pentopyranosyl)nucleotid-Rückgraten

Stefan Pitsch, Esteban Pombo-Villar, Albert Eschenmoser

Journal:

Helvetica Chimica Acta

Year:

1994

File:

PDF, 2.40 MB

1994

20

Synthesis of Cyclopenta[b]indol-1-ones and Carbazol-4-ones from N-(2-Halophenyl)-Substituted Enaminones by Intramolecular Heck Reaction

Ulrik S. Sørensen, Esteban Pombo-Villar

Journal:

Helvetica Chimica Acta

Year:

2004

Language:

english

File:

PDF, 119 KB

english, 2004

21

Solid phase synthesis of phosphonoserine isosteres of phosphoserine peptides

Gideon Shapiro, Dieter Buechler, Albert Enz, Esteban Pombo-Villar

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 278 KB

english, 1994

22

Combined Fmoc-Alloc strategy for a general solid phase synthesis of phosphoserine peptides

Gideon Shapiro, Dieter Büchler, Claudio Dalvit, Maria del Carmen Fernandez, Berta Gomez-Lor, Esteban Pombo-Villar, Urs Stauss, Robert Swoboda

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 371 KB

english, 1996

23

Solution phase synthesis of esters within a micro reactor

Charlotte Wiles, Paul Watts, Stephen J Haswell, Esteban Pombo-Villar

Journal:

Year:

2003

Language:

english

File:

PDF, 312 KB

english, 2003

24

Copper-free palladium-catalyzed sonogashira-type coupling of aryl halides and 1-aryl-2-(trimethylsilyl)acetylenes

Ulrik S. Sørensen, Esteban Pombo-Villar

Journal:

Year:

2005

Language:

english

File:

PDF, 229 KB

english, 2005

25

The preparation and reaction of enolates within micro reactors

Charlotte Wiles, Paul Watts, Stephen J. Haswell, Esteban Pombo-Villar

Journal:

Year:

2005

Language:

english

File:

PDF, 620 KB

english, 2005

26

Microwave promoted energy-efficient N-formylation with aqueous formic acid

Ajay K. Bose, Subhendu N. Ganguly, Maghar S. Manhas, Atri Guha, Esteban Pombo-Villars

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 77 KB

english, 2006

27

Neolignans from Virola elongata

Juan C.V. Martinez, Luis E.S. Cuca, Antonio J.M. Santana, Esteban Pombo-Villar, Bernard T. Golding

Journal:

Year:

1985

Language:

english

File:

PDF, 283 KB

english, 1985

28

Asymmetric synthesis of a protected phosphonate isostere of phosphothreonine for solid-phase peptide synthesis

María Ruiz, Vicente Ojea, Gideon Shapiro, Hans-Peter Weber, Esteban Pombo-Villar

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 374 KB

english, 1994

29

Synthesis of both D- and L-Fmoc-Abu[PO(OCH2CHCH2)2]-OH for solid phase phosphonopeptide synthesis

Gideon Shapiro, Dieter Buechler, Vicente Ojea, Esteban Pombo-Villar, Maria Ruiz, Hans-Peter Weber

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 278 KB

english, 1993

30

Enantiospecific synthesis of 2-amino-3-methyl-4-phosphonobutanoic acids via 14-addition of lithiated Schöllkopf anion to prop-2-enylphosphonates

Vicente Ojea, María Ruiz, Gideon Shapiro, Esteban Pombo-Villar

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 346 KB

english, 1994

31

The regioselective preparation of 1,3-diketones

Charlotte Wiles, Paul Watts, Stephen J. Haswell, Esteban Pombo-Villar

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 89 KB

english, 2002

32

Corrigendum to “The regioselective preparation of 1,3-diketones”: [Tetrahedron Lett. 43 (2002) 2945–2948]

Charlotte Wiles, Paul Watts, Stephen J. Haswell, Esteban Pombo-Villar

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 29 KB

english, 2002

33

7-Oxa[2.2.1]bicycloheptane-2,3-dicarboxylic acid derivatives as phosphatase inhibitors

Albert Enz, Gerhard Zenke, Esteban Pombo-Villar

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 333 KB

english, 1997

34

Combined Fmoc-Alloc strategy for a general SPPS of phosphoserine peptides; preparation of phosphorylation-dependent tau antisera

Gideon Shapiro, Dieter Büchler, Claudio Dalvit, Peter Frey, Maria del Carmen Fernández, Berta Gomez-Lor, Esteban Pombo-Villar, Urs Stauss, Robert Swoboda, Caroline Waridel

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 875 KB

english, 1997

35

Electrochemical effects related to synthesis in micro reactors operating under electrokinetic flow

Paul Watts, Stephen J Haswell, Esteban Pombo-Villar

Journal:

Chemical Engineering Journal

Year:

2004

Language:

english

File:

PDF, 88 KB

english, 2004

36

The regioselective preparation of 1,3-diketones within a micro reactor

Wiles, Charlotte, Watts, Paul, Haswell, Stephen J., Pombo-Villar, Esteban

Journal:

Chemical Communications

Year:

2002

Language:

english

File:

PDF, 123 KB

english, 2002

37

Stereoisomerism and muscarinic receptor agonists: synthesis and effects of the stereoisomers of 3-[5-(3-amino-1,2,4-oxadiazol)yl]-1-azabicyclo[2.2.1]heptane

Esteban Pombo-Villar, Karl-Heinz Wiederhold, Guadalupe Mengod, JoséM. Palacios, Porntip Supavilai, Hendrikus W.G.M. Boddeke

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.15 MB

english, 1992

38

Class II pyrethroids: Noninhibitors calcineurin

Albert Enz, Esteban Pombo-Villar

Journal:

Biochemical Pharmacology

Year:

1997

Language:

english

File:

PDF, 406 KB

english, 1997

39

Structures of ?- and ?-turmerone

Golding, Bernard T., Pombo-Villar, Esteban

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1992

Language:

english

File:

PDF, 765 KB

english, 1992

40

Selective functionalisation of 1,3-dienes via organosulphur intermediates

Golding, Bernard T., Pombo-Villar, Esteban, Samuel, Christopher J.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1985

Language:

english

File:

PDF, 189 KB

english, 1985

41

The aldol reaction of silyl enol ethers within a micro reactor

Wiles, Charlotte, Watts, Paul, Haswell, Stephen J., Pombo-Villar, Esteban

Journal:

Year:

2001

Language:

english

File:

PDF, 69 KB

english, 2001

42

Conjugate Additions of 1-Propenylphosphonates to Metalated Schöllkopf's Bis-lactim Ether: Stereocontrolled Access to 2-Amino-3-methyl-4-phosphonobutanoic Acids

Ojea, Vicente, Ruiz, María, Shapiro, Gideon, Pombo-Villar, Esteban

Journal:

Journal of Organic Chemistry

Year:

2000

Language:

english

File:

PDF, 230 KB

english, 2000

43

The Application of Microreactor Technology for the Synthesis of 1,2-Azoles

Wiles, Charlotte, Watts, Paul, Haswell, Stephen J., Pombo-Villar, Esteban

Journal:

Organic Process Research & Development

Year:

2004

Language:

english

File:

PDF, 69 KB

english, 2004

44

The synthesis of peptides using micro reactors

Watts, Paul, Wiles, Charlotte, Haswell, Stephen J., Pombo-Villar, Esteban, Styring, Peter

Journal:

Chemical Communications

Year:

2001

Language:

english

File:

PDF, 51 KB

english, 2001

45

1,4-Addition of enolates to ?,?-unsaturated ketones within a micro reactor

Wiles, Charlotte, Watts, Paul, Haswell, Stephen J., Pombo-Villar, Esteban

Journal:

Year:

2002

Language:

english

File:

PDF, 83 KB

english, 2002

46

Stereoselective alkylation of an Evans auxiliary derivative within a pressure-driven micro reactor

Wiles, Charlotte, Watts, Paul, Haswell, Stephen J., Pombo-Villar, Esteban

Journal:

Year:

2004

Language:

english

File:

PDF, 141 KB

english, 2004

47

On-chip separation of peptides prepared within a micro reactor

George, Vinod, Watts, Paul, Haswell, Stephen J., Pombo-Villar, Esteban

Journal:

Chemical Communications

Year:

2003

Language:

english

File:

PDF, 173 KB

english, 2003

48

Synthesis of N-Arylrolipram Derivatives - Potent and Selective Phosphodiesterase-IV Inhibitors - by Copper Catalyzed Lactam-Aryl Halide Coupling

W. Joachim Demnitz, F., Aebischer, Esther, Bacher, Edmond, H. Keller, Thomas, Kurzmeyer, Miriam, L. Ortiz, Marta, Pombo-Villar, Esteban, Weber, Hans-Peter

Journal:

Year:

1998

Language:

english

File:

PDF, 148 KB

english, 1998

49

Synthesis and Structure-Activity Relationship of N-Arylrolipram Derivatives as Inhibitors of PDE4 Isozymes.

KELLER, Thomas H., BRAY-FRENCH, Katharine, DEMNITZ, F.W. Joachim, MÜLLER, Thomas, POMBO-VILLAR, Esteban, WALKER, Christoph

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2001

Language:

english

File:

PDF, 117 KB

english, 2001

50

Enantiodivergent Synthesis of (R)- and (S)-Rolipram

Demnitz, Joachim, LaVecchia, Luigi, Bacher, Edmond, Keller, Thomas, Müller, Thomas, Schürch, Friedrich, Weber, Hans-Peter, Pombo-Villar, Esteban

Journal:

Year:

1998

Language:

english

File:

PDF, 466 KB

english, 1998

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